Catalog No: OPED00051
Size:50 ug
Price: $240.00
SKU
OPED00051
Availability: Domestic: within 1-2 week delivery | International: 1-2 week
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Datasheets/Manuals | Printable datasheet for Grp94 Recombinant Protein (Canine) (OPED00051) (OPED00051) |
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Predicted Species Reactivity | Canis lupus|Dog |
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Product Format | Liquid. In 20mM MOPS, pH 7.5, containing 0.5mM EDTA. |
Host | Sf21 cells |
Application | WB |
Additional Information | Grp94 (Glucose-regulated protein 94) is an abundant resident endoplasmic reticulum (ER) lumenal stress protein, which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. Grp94 expression is upregulated by stress conditions such as glucose starvation and heat shock, which promote protein misfolding or unfolding. In addition to a homeostatic role in protein folding and assembly, Grp94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. |
Reconstitution and Storage | Store at -80C |
Purification | Purified by multi-step chromatography. |
Purity | >90% (SDS-PAGE; Western blot) |
Application Info | Western blot control. |
Gene Symbol | HSP90B1 |
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Gene Full Name | heat shock protein 90 beta family member 1 |
Alias Symbols | 94 kDa glucose-regulated protein;endoplasmin;GRP94;GRP-94;heat shock protein 90 kDa beta member 1;heat shock protein 90kDa beta (Grp94), member 1;HSP90 beta;TRA1;tumor rejection antigen (gp96) 1;tumor rejection antigen 1. |
NCBI Gene Id | 404019 |
Protein Name | Endoplasmin |
Description of Target | Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity). |
Uniprot ID | P41148 |
Protein Accession # | NP_065390.1 |
Nucleotide Accession # | NM_020529.2 |
Protein Size (# AA) | Recombinant |
Molecular Weight | 94 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
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