Catalog No: ARP54750_P050
Price: $0.00
SKU
ARP54750_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.

GRK5 Antibody - middle region (ARP54750_P050)

Rating:
93% of 100
Datasheets/ManualsPrintable datasheet for anti-GRK5 (ARP54750_P050) antibody
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human GRK5
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Yeast: 79%; Zebrafish: 86%
Peptide SequenceSynthetic peptide located within the following region: FYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEG
Concentration0.5 mg/ml
Blocking PeptideFor anti-GRK5 (ARP54750_P050) antibody is Catalog # AAP54750 (Previous Catalog # AAPP31545)
ReferenceLiggett,S.B., (2008) Nat. Med. 14 (5), 510-517
Publications

The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5. Sci Rep. 6, 33231 (2016). 27618959

Gene SymbolGRK5
Gene Full NameG protein-coupled receptor kinase 5
Alias SymbolsGPRK5, FP2025
NCBI Gene Id2869
Protein NameG protein-coupled receptor kinase 5
Description of TargetGRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP34947
Protein Accession #NP_005299
Nucleotide Accession #NM_005308
Protein Size (# AA)590
Molecular Weight68kDa
Protein InteractionsTBXA2R; USP47; C1QBP; YWHAB; XRCC5; UBTF; UBC; TUFM; NR2F1; TCOF1; SRPK1; SPTBN1; SPTAN1; SMARCA1; SKP1; SRSF1; RPL4; RPL3; RBMS1; PSMD11; PSMD2; PSMC6; PSMC2; PSMC1; PRKDC; PPP2R2A; PNN; PIP4K2A; PIP; NFIB; NCL; NCBP1; MYO9B; MYO1C; MYH10; MYH9; MYCN; MA
  1. What is the species homology for "GRK5 Antibody - middle region (ARP54750_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish".

  2. How long will it take to receive "GRK5 Antibody - middle region (ARP54750_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "GRK5 Antibody - middle region (ARP54750_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GRK5 Antibody - middle region (ARP54750_P050)"?

    This target may also be called "GPRK5, FP2025" in publications.

  5. What is the shipping cost for "GRK5 Antibody - middle region (ARP54750_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GRK5 Antibody - middle region (ARP54750_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GRK5 Antibody - middle region (ARP54750_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "68kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GRK5 Antibody - middle region (ARP54750_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GRK5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GRK5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GRK5"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GRK5"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GRK5"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GRK5"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:GRK5 Antibody - middle region (ARP54750_P050)
Your Rating
We found other products you might like!