- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-GRIN2A (OASG05080) antibody |
|---|
| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | IHC, IF |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | Synthesized peptide derived from human NMDAEpsilon1/2 around the phosphorylation site of Y1246/1252. Location: 1190-1270aa. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Target Post-Translational Modification | Phospho-Tyr1246/1252 |
| Specificity | Phospho-NMDAEpsilon1/2 (Tyr1246/1252) Polyclonal Antibody detects endogenous levels of NMDAEpsilon1/2 protein only when phosphorylated at Y1246/1252. |
| Application Info | IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; |
| Gene Symbol | GRIN2A, GRIN2B |
|---|---|
| Gene Full Name | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
| Alias Symbols | LKS, EPND, FESD, NR2A, GluN2A, NMDAR2A |
| NCBI Gene Id | 2903; 2904; 14811; 14812; 24409; 24410 |
| Description of Target | This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. |
| Uniprot ID | Q12879, Q13224, P35436, Q01097, Q00959, Q00960 |
| Molecular Weight | 166 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "GRIN2A Antibody (Phospho-Tyr1246/1252) (OASG05080)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
-
How long will it take to receive "GRIN2A Antibody (Phospho-Tyr1246/1252) (OASG05080)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
-
What buffer format is "GRIN2A Antibody (Phospho-Tyr1246/1252) (OASG05080)" provided in?
This item is provided in "Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "GRIN2A Antibody (Phospho-Tyr1246/1252) (OASG05080)"?
This target may also be called "LKS, EPND, FESD, NR2A, GluN2A, NMDAR2A" in publications.
-
What is the shipping cost for "GRIN2A Antibody (Phospho-Tyr1246/1252) (OASG05080)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "GRIN2A Antibody (Phospho-Tyr1246/1252) (OASG05080)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "GRIN2A Antibody (Phospho-Tyr1246/1252) (OASG05080)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "166 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "GRIN2A Antibody (Phospho-Tyr1246/1252) (OASG05080)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "GRIN2A, GRIN2B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "GRIN2A, GRIN2B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "GRIN2A, GRIN2B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "GRIN2A, GRIN2B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "GRIN2A, GRIN2B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "GRIN2A, GRIN2B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.