GRIK2 Antibody - N-terminal region : HRP (ARP35515_T100-HRP)

Catalog No: ARP35515_T100-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: IHC, WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GRIK2
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: PDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-GRIK2 (ARP35515_T100-HRP) antibody is Catalog # AAP35515 (Previous Catalog # AAPP07288)
• Reference: Delorme,R., et al., (2004) 15 (4), 699-702
• Publications:

  Funk, J. A. et al. Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid. J. Am. Soc. Nephrol. 25, 1187-97 (2014). IHC, Mouse, Human, Zebrafish, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig 24511141

Target Info

• Gene Symbol: GRIK2
• Gene Full Name: Glutamate receptor, ionotropic, kainate 2
• Alias Symbols: EAA4, GLR6, MRT6, GLUK6, GLUR6, GluK2
• NCBI Gene Id: 2898
• Protein Name: Glutamate receptor, ionotropic kainate 2
• Description of Target: The GRIK2 gene encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus. The structure and function of the encoded protein is changed by RNA editing.
• Uniprot ID: Q13002
• Protein Size (# AA): 908
• Molecular Weight: 102kDa
• Protein Interactions: CALCOCO1; TRIM25; PICK1; DLG4; LIN7B; GRID2; PRKAA1; SDCBP; CTNND1; DLG1; GRIK5; GRIK4; DLG3; CASK; GRIA1; GRIK2; CTNNB1; CDH2; GRIP1; GRIA2;