- Gene Symbol:
- GRHPR
- Official Gene Full Name:
- Glyoxylate reductase/hydroxypyruvate reductase
- NCBI Gene Id:
- 9380
- Protein Name:
- Glyoxylate reductase/hydroxypyruvate reductase
- Swissprot Id:
- Q9UBQ7
- Protein Accession #:
- NP_036335
- Nucleotide Accession #:
- NM_012203
- Alias Symbols:
- GLXR, PH2, GLYD
- Replacement Item:
- This antibody may replace item sc-128735 from Santa Cruz Biotechnology.
- Description of Target:
- GRHPR is an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Protein Size (# AA):
- 328
- Molecular Weight:
- 36kDa
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Purification:
- Affinity Purified
- Application:
- IHC, WB
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express GRHPR.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express GRHPR.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human GRHPR
- Predicted Species Reactivity:
- Dog, Horse, Human, Pig, Rabbit, Rat
- Tested Species Reactivity:
- Human
- Predicted Homology Based on Immunogen Sequence:
- Dog: 100%; Horse: 86%; Human: 100%; Pig: 79%; Rabbit: 93%; Rat: 91%
- Complete computational species homology data:
- Anti-GRHPR (ARP48317_P050)
- Peptide Sequence:
- Synthetic peptide located within the following region: EPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDH
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Concentration:
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Protein Interactions:
- GLS2; CDC7; UBC; PTH2R; FOS; LIG4; SUCLA2; PGM1; HSD17B4; CXADR; SLC25A5; ACOX1; LSM1;
- Blocking Peptide:
- For anti-GRHPR (ARP48317_P050) antibody is Catalog # AAP48317 (Previous Catalog # AAPY01693)
- Datasheets/Manuals:
- Printable datasheet for anti-GRHPR (ARP48317_P050) antibody
- Target Reference:
- Takayama,T., (2007) Nephrol. Dial. Transplant. 22 (8), 2371-2374
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