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GOT2 Antibody - N-terminal region (ARP43517_P050)

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100 ul
$289.00
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Conjugation Options

ARP43517_P050-FITC Conjugated

ARP43517_P050-HRP Conjugated

ARP43517_P050-Biotin Conjugated

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Gene Symbol:
GOT2
Official Gene Full Name:
Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
NCBI Gene Id:
2806
Protein Name:
Aspartate aminotransferase, mitochondrial
Swissprot Id:
P00505
Protein Accession #:
NP_002071
Nucleotide Accession #:
NM_002080
Alias Symbols:
FLJ40994, kat4, kativ, mitaat, KAT4, KATIV, mitAAT
Description of Target:
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Size (# AA):
430
Molecular Weight:
45kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express GOT2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express GOT2.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human GOT2
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-GOT2 (ARP43517_P050)
Peptide Sequence:
Synthetic peptide located within the following region: VEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEA
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
FUS; UBC; NEDD8; MDM2; CDK2; CCL21; GLRX; GAPDH; APCS; AI837181; HDAC5; PSMD4; THOC7; ZDHHC6; GLUD1; HSPA8; PC; MDH2; CTNNBIP1; MPG;
Blocking Peptide:
For anti-GOT2 (ARP43517_P050) antibody is Catalog # AAPY01352
Datasheets/Manuals:
Printable datasheet for anti-GOT2 (ARP43517_P050) antibody
Target Reference:
Tsai,S.J., Psychiatr. Genet. 17 (5), 314 (2007)
Publications:

Povlsen, J. A. et al. Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One 8, e64093 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 23704975

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