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Catalog No: OPCD01509
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OPCD01509
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Datasheets/ManualsPrintable datasheet for GOT1 Recombinant Protein (OPCD01509)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Met1-Gln413
::Subcellular Location: Cytoplasm
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolGOT1
Gene Full Nameglutamic-oxaloacetic transaminase 1
Alias Symbolsaspartate aminotransferase 1;aspartate aminotransferase, cytoplasmic;aspartate transaminase 1;AST1;ASTQTL1;cAspAT;cCAT;cysteine aminotransferase, cytoplasmic;cysteine transaminase, cytoplasmic;GIG18;glutamate oxaloacetate transaminase 1;glutamic-oxaloacetic transaminase 1, soluble;growth-inhibiting protein 18;testis secretory sperm-binding protein Li 196a;transaminase A.
NCBI Gene Id2805
Protein NameAspartate aminotransferase, cytoplasmic
Description of TargetBiosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
Uniprot IDP17174
Protein Accession #NP_002070.1
Nucleotide Accession #NM_002079.2
Protein Size (# AA)Met1~Gln413
Molecular Weight44kDa
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