Size:100 ul
Special Price $229.00 Regular Price $319.00
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ARP48205_P050
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Conjugation Options

ARP48205_P050-FITC Conjugated

ARP48205_P050-HRP Conjugated

ARP48205_P050-Biotin Conjugated

GOT1 Antibody - N-terminal region (ARP48205_P050)

Catalog#: ARP48205_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-367196 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human GOT1
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 85%
Complete computational species homology data Anti-GOT1 (ARP48205_P050)
Peptide Sequence Synthetic peptide located within the following region: MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWV
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-GOT1 (ARP48205_P050) antibody is Catalog # AAP48205 (Previous Catalog # AAPP13024)
Datasheets/Manuals Printable datasheet for anti-GOT1 (ARP48205_P050) antibody
Sample Type Confirmation

GOT1 is supported by BioGPS gene expression data to be expressed in NCIH226

Target Reference Inoue,K., Diabetes Res. Clin. Pract. 79 (3), E4-E7 (2008)
Publications

Povlsen, J. A. et al. Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One 8, e64093 (2013). IHC, WB, Cow, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 23704975

Takeda, K., Ishida, A., Takahashi, K. & Ueda, T. Synaptic vesicles are capable of synthesizing the VGLUT substrate glutamate from -alpha-ketoglutarate for vesicular loading. J. Neurochem. 121, 184-96 (2012). IHC, WB, Cow, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 22309504

Gene Symbol GOT1
Official Gene Full Name Glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
Alias Symbols GIG18, ASTQTL1
NCBI Gene Id 2805
Protein Name Aspartate aminotransferase, cytoplasmic
Description of Target Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enz
Swissprot Id P17174
Protein Accession # NP_002070
Nucleotide Accession # NM_002079
Protein Size (# AA) 413
Molecular Weight 46kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express GOT1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express GOT1.
Protein Interactions UBC; CHRAC1; SBDS; UBE2H; TYMS; MTAP; IDH1; HPRT1; ANXA6; ABI3BP; EGFR; TMEM120A; PC;
  1. What is the species homology for "GOT1 Antibody - N-terminal region (ARP48205_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish".

  2. How long will it take to receive "GOT1 Antibody - N-terminal region (ARP48205_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "GOT1 Antibody - N-terminal region (ARP48205_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GOT1 Antibody - N-terminal region (ARP48205_P050)"?

    This target may also be called "GIG18, ASTQTL1" in publications.

  5. What is the shipping cost for "GOT1 Antibody - N-terminal region (ARP48205_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GOT1 Antibody - N-terminal region (ARP48205_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GOT1 Antibody - N-terminal region (ARP48205_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "46kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GOT1 Antibody - N-terminal region (ARP48205_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "GOT1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GOT1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GOT1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GOT1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GOT1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GOT1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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