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| Datasheets/Manuals | Printable datasheet for Type IV Collagen Antibody : Biotin (OASB02744) |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Mouse, Rat, Canine, Chicken, Chinchilla, Equine, Guinea Pig, Japanese Macaque, Porcine, Rabbit, Sheep, Tree Shrew |
| Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide |
| Clonality | Polyclonal |
| Host | Goat |
| Conjugation | Biotin |
| Application | EM, FC, ICC, IHC-F, IHC-P, IP, WB |
| Additional Information | Description: Pooled antisera from goats hyperimmunized with type IV collagen; purified by affinity chromatography on type IV collagen covalently linked to agarose; reacts with conformational determinants on type IV collagen; cross-adsorbed against Collagen types I, II, III, V, and VI for minimal reactivity |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | Type IV collagen |
| Concentration | 0.4 mg/mL |
| Specificity | Type IV Collagen |
| Gene Symbol | COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6 |
|---|---|
| Gene Full Name | collagen type IV alpha 1 chain |
| Alias Symbols | BSVD, BSVD1, RATOR, PADMAL, COL4A1s |
| NCBI Gene Id | 1282; 1284; 1285; 1286; 1287; 1288 |
| Protein Name | collagen alpha-1(IV) chain |
| Description of Target | This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. |
| Uniprot ID | P02462, P08572, Q01955, P53420, P29400, Q14031 |
| Protein Accession # | NP_001290039.1 |
| Nucleotide Accession # | NM_001303110.1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Type IV Collagen Antibody : Biotin (OASB02744)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Mouse, Rat, Canine, Chicken, Chinchilla, Equine, Guinea Pig, Japanese Macaque, Porcine, Rabbit, Sheep, Tree Shrew".
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How long will it take to receive "Type IV Collagen Antibody : Biotin (OASB02744)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "Type IV Collagen Antibody : Biotin (OASB02744)" provided in?
This item is provided in "Liquid. Phosphate buffered saline containing 0.1% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Type IV Collagen Antibody : Biotin (OASB02744)"?
This target may also be called "BSVD, BSVD1, RATOR, PADMAL, COL4A1s" in publications.
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What is the shipping cost for "Type IV Collagen Antibody : Biotin (OASB02744)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Type IV Collagen Antibody : Biotin (OASB02744)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Type IV Collagen Antibody : Biotin (OASB02744)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Type IV Collagen Antibody : Biotin (OASB02744)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.