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Goat Anti-PXR / NR1I2 Antibody (OAEB01986)

100 ug
$349.00
In Stock
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Gene Symbol:
NR1I2
NCBI Gene Id:
8856
Protein Name:
Nuclear receptor subfamily 1 group I member 2
Swissprot Id:
O75469
Protein Accession #:
NP_003880.3
Alias Symbols:
PXR, NR1I2, nuclear receptor subfamily 1, group I, member 2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, SAR, SXR, orphan nuclear receptor, pregnane X receptor, steroid and xenobiotic receptor
Host:
Goat
Clonality:
Polyclonal
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NR1I2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NR1I2.
Immunogen:
This antibody is expected to recognize all reported isoforms (NP_071285.1; NP_148934.1; NP_003880.3).
Predicted Species Reactivity:
Dog, Guinea Pig, Human, Pig
Predicted Homology Based on Immunogen Sequence:
Dog: 80%; Guinea Pig: 76%; Human: 100%; Pig: 86%
Complete computational species homology data:
NR1I2 Antibody (OAEB01986)
Peptide Sequence:
EQFAITLKSYIECNR
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals:
Printable datasheet for anti-NR1I2 antibody - OAEB01986
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:4000.
Western Blot: Approx. 48kDa band observed in lysates of cell line HepG2 (calculated MW of 49.8kDa according to NP_003880.3). Recommended concentration: 1-3ug/ml.
An additional band of unknown identity was also consistently observed at 35kDa. This band was successfully blocked by incubation with the immunizing peptide.
Additional Information:
Reactivity Info: Tested: Human; Expected: Human
Target Reference:
* Thakur JK, Arthanari H, Yang F, Pan SJ, Fan X, Breger J, Frueh DP, Gulshan K, Li DK, Mylonakis E, Struhl K, Moye-Rowley WS, Cormack BP, Wagner G, Näär AM.; A nuclear receptor-like pathway regulating multidrug resistance in fungi.; Nature 2008 Apr 452 (7187): 604-9.; Pubmed 18385733

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