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Goat Anti-MEL18 / PCGF2 Antibody (OAEB01334)

100 ug
In Stock
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Predicted Species Reactivity:
Cow, Dog, Human, Mouse, Rabbit, Rat
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Additional Information:
Reactivity Info: Tested: Human; Expected: Human, Dog, Cow
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Gene Symbol:
NCBI Gene Id:
Protein Name:
Polycomb group RING finger protein 2
Swissprot Id:
Protein Accession #:
Alias Symbols:
PCGF2, MEL-18, polycomb group ring finger 2, RNF110, ZNF144, ring finger protein 110, zinc finger protein 144, MGC10545
Replacement Item:
This antibody may replace item sc-8904 from Santa Cruz Biotechnology.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PCGF2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PCGF2.
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 90%; Rabbit: 100%; Rat: 90%
Complete computational species homology data:
PCGF2 Antibody (OAEB01334)
Peptide Sequence:
Printable datasheet for anti-PCGF2 antibody - OAEB01334
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:16000.
Western Blot: Approx 40 kDa band observed in Human Lung lysates (calculated MW of 37.8kDa according to NP_009075.1). Recommended for use at 1-2ug/ml.
Target Reference:
* Endoh M, Endo TA, Endoh T, Fujimura Y, Ohara O, Toyoda T, Otte AP, Okano M, Brockdorff N, Vidal M, Koseki H.; Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.; Development. 2008 Apr;135(8):1513-24.; Pubmed 18339675
* Miki J, Fujimura Y, Koseki H, Kamijo T.; Polycomb complexes regulate cellular senescence by repression of ARF in cooperation with E2F3.; Genes Cells. 2007 Dec;12(12):1371-82.; Pubmed 18076574
* Elderkin S, Maertens GN, Endoh M, Mallery DL, Morrice N, Koseki H, Peters G, Brockdorff N, Hiom K.; A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin.; Mol Cell. 2007 Oct 12;28(1):107-20.; Pubmed 17936708
* Xi S, Zhu H, Xu H, Schmidtmann A, Geiman TM, Muegge K.; Lsh controls Hox gene silencing during development.; Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14366-71.; Pubmed 17726103
* Ishida A, Asano H, Hasegawa M, Koseki H, Ono T, Yoshida MC, Taniguchi M, Kanno M.; Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif.; Gene. 1993 Jul 30;129(2):249-55.; Pubmed 8325509

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