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Goat Anti-KCNJ1 / ROMK Antibody (OAEB02289)

100 ug
$299.00
In Stock
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Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Mouse, Pig, Rabbit, Rat
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clonality:
Polyclonal
Host:
Goat
Application:
WB
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Gene Symbol:
KCNJ1
NCBI Gene Id:
3758
Protein Name:
ATP-sensitive inward rectifier potassium channel 1
Swissprot Id:
P48048
Protein Accession #:
NP_000211.1
Alias Symbols:
KCNJ1, potassium inwardly-rectifying channel, subfamily J, member 1, KIR1.1, ROMK, ROMK1, ATP-regulated potassium channel ROM-K, ATP-sensitive inward rectifier potassium channel 1, OTTHUMP00000045938, inwardly rectifying K+ channel, potassium inwar
Replacement Item:
This antibody may replace item sc-10692 from Santa Cruz Biotechnology.
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express KCNJ1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express KCNJ1.
Immunogen:
This antibody is expected to recognize reported isoforms NP_722449.2 and NP_000211. The following reported variants represent identical protein: NP_722451.1, NP_722449.2, NP_722450.1, NP_722448.1.
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%
Complete computational species homology data:
KCNJ1 Antibody (OAEB02289)
Peptide Sequence:
C-DQININFVVDAGNEN
Datasheets/Manuals:
Printable datasheet for anti-KCNJ1 antibody - OAEB02289
Application Info:
Peptide ELISA: antibody detection limit dilution 1:8000.
Western Blot: Approx. 45kDa band observed in Human, Mouse and Rat Kidney lysates (calculated MW of 44.8kDa according to NP_000211.1). Recommended concentration: 1-3ug/ml.
Target Reference:
* Ji W, Foo JN, O'Roak BJ, Zhao H, Larson MG, Simon DB, Newton-Cheh C, State MW, Levy D, Lifton RP.; Rare independent mutations in renal salt handling genes contribute to blood pressure variation.; Nat. Genet. 2008 May 40 (5): 592-9.; Pubmed 18391953

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