Catalog No: OAEB00866 (Formerly GWB-F598CD)
Size:100UG
Price: $379.00
SKU
OAEB00866
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)
Product Info
Predicted Species ReactivityHuman
Product FormatSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
ClonalityPolyclonal
HostGoat
ApplicationWB, ICC, IHC, CHIP
Additional InformationReactivity Info: Tested: Human; Expected: Human, Dog, Pig
::Description: This antibody is expected to recognize both reported isoforms (NP_054728.2 and NP_001107849.1)
Reconstitution and StorageAliquot and store at -20C. Minimize freezing and thawing.
ImmunogenFOXP3
PurificationAmmonium Sulfate Precipitated; Affinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 92%; Horse: 100%; Human: 100%; Pig: 100%; Sheep: 100%
Peptide SequenceSQRPSRCSNPTPGP
Concentration0.5 mg/ml
Application InfoPeptide ELISA: antibody detection limit dilution 1:8000.
Western Blot: This antibody has been successfully used in WB on human T regulatory cells.
Immunohistochemistry: In paraffin embedded Human Tonsil, stains nuclei of some cells in the interfollicular area. Recommended concentration, 0.3-1 ug/ml.
Chromatin immunoprecipitation: This antibody has been successfully used in ChIP on activated human T cells.
Immunocytochemistry: CD25-sorted (Treg) human blood cells with nuclear speckled staining. Recommended concentration 2-4ug/ml for overnight staining.
Reference* Mansour H, Homs S, Desvaux D, Badoual C, Dahan K, Matignon M, Audard V, Lang P, Grimbert P.; Intragraft levels of Foxp3 mRNA predict progression in renal transplants with borderline change.; J Am Soc Nephrol. 2008 Dec;19(12):2277-81.; Pubmed 18667728
* Banham AH, Brown PJ, Lyne L, Schulze HJ, Hallermann C.; Is FOXP3 expressed in cutaneous T-cell lymphomas?; Eur J Haematol. 2008 Jan;80(1):90-1.; Pubmed 18036183
* Baumforth KR, Birgersdotter A, Reynolds GM, Wei W, Kapatai G, Flavell JR, Kalk E, Piper K, Lee S, Machado L, Hadley K, Sundblad A, Sjoberg J, Bjorkholm M, Porwit AA, Yap LF, Teo S, Grundy RG, Young LS, Ernberg I, Woodman CB, Murray PG.; Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cells.; Am J Pathol. 2008 Jul;173(1):195-204.; Pubmed 18502823
* Radulovic S, Jacobson MR, Durham SR, Nouri-Aria KT.; Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa.; J Allergy Clin Immunol. 2008 Jun;121(6):1467-72, 1472.e1.; Pubmed 18423565
* Ward FJ, Hall AM, Cairns LS, Leggat AS, Urbaniak SJ, Vickers MA, Barker RN.; Clonal regulatory T cells specific for a red blood cell autoantigen in human autoimmune hemolytic anemia.; Blood. 2008 Jan 15;111(2):680-7.; Pubmed 17761830
* Nakamura T, Shima T, Saeki A, Hidaka T, Nakashima A, Takikawa O, Saito S.; Expression of indoleamine 2, 3-dioxygenase and the recruitment of Foxp3-expressing regulatory T cells in the development and progression of uterine cervical cancer.; Cancer Sci. 2007 Jun;98(6):874-81.; Pubmed 17433037
* Soler D, Chapman TR, Poisson LR, Wang L, Cote-Sierra J, Ryan M, McDonald A, Badola S, Fedyk E, Coyle AJ, Hodge MR, Kolbeck R.; CCR8 expression identifies CD4 memory T cells enriched for FOXP3+ regulatory and Th2 effector lymphocytes.; J Immunol. 2006 Nov 15;177(10):6940-51.; Pubmed 17082609
* Kitamura H, Torigoe T, Honma I, Sato E, Asanuma H, Hirohashi Y, Sato N, Tsukamoto T.; Effect of human leukocyte antigen class I expression of tumor cells on outcome of intravesical instillation of bacillus calmette-guerin immunotherapy for bladder cancer.; Clin Cancer Res. 2006 Aug 1;12(15):4641-4.; Pubmed 16899613
* Appay V, Jandus C, Voelter V, Reynard S, Coupland SE, Rimoldi D, Lienard D, Guillaume P, Krieg AM, Cerottini JC, Romero P, Leyvraz S, Rufer N, Speiser DE.; New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site.; J Immunol. 2006 Aug 1;177(3):1670-8.; Pubmed 16849476
* Chatila TA, Blaeser F, Ho N, Lederman HM, Voulgaropoulos C, Helms C, Bowcock AM.; JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome.; J Clin Invest. 2000 Dec;106(12):R75-81.; Pubmed 11120765
Gene SymbolFOXP3
Gene Full Nameforkhead box P3
Alias SymbolsAIID;DIETER;forkhead box protein P3;FOXP3delta7;immune dysregulation, polyendocrinopathy, enteropathy, X-linked;immunodeficiency, polyendocrinopathy, enteropathy, X-linked;IPEX;JM2;PIDX;XPID.
NCBI Gene Id50943
Protein NameForkhead box protein P3
Uniprot IDQ9BZS1
Protein Accession #NP_054728.2
Molecular Weight47.2; 43.4
  1. What is the species homology for "Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)" provided in?

    This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)"?

    This target may also be called "AIID;DIETER;forkhead box protein P3;FOXP3delta7;immune dysregulation, polyendocrinopathy, enteropathy, X-linked;immunodeficiency, polyendocrinopathy, enteropathy, X-linked;IPEX;JM2;PIDX;XPID." in publications.

  5. What is the shipping cost for "Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "47.2; 43.4".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Goat Anti-FOXP3 / SCURFIN Antibody (OAEB00866)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "FOXP3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "FOXP3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "FOXP3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "FOXP3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "FOXP3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "FOXP3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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