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Goat Anti-CIAS1 / cryopyrin (C Terminus) Antibody (OAEB00821)

100 ug
$349.00
In Stock
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Gene Symbol:
NLRP3
NCBI Gene Id:
114548
Protein Name:
NACHT, LRR and PYD domains-containing protein 3
Swissprot Id:
Q96P20
Protein Accession #:
NP_001073289.1
Alias Symbols:
NLRP3, CIAS1, FCU, MWS, FCAS, NALP3, C1orf7, PYPAF1, AII/AVP, AGTAVPRL, CRYOPYRIN, cold autoinflammatory syndrome 1, cryopyrin, Muckle-Wells syndrome, chromosome 1 open reading frame 7, PYRIN-containing APAF1-like protein 1, neuronal apopt
Replacement Item:
This antibody may replace item sc-134306 from Santa Cruz Biotechnology.
Host:
Goat
Clonality:
Polyclonal
Application:
ELISA, FC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NLRP3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NLRP3.
Predicted Species Reactivity:
Dog, Horse, Human, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Dog: 90%; Horse: 92%; Human: 100%; Rabbit: 92%; Rat: 92%
Complete computational species homology data:
NLRP3 antibody - C-terminal region (OAEB00821)
Peptide Sequence:
C-EKPELTVVFEPSW
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals:
Printable datasheet for anti-NLRP3 antibody - OAEB00821
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:32000.
Western Blot: No signal obtained yet but low background observed in Daudi, A431, Jurkat, U937 and MOLT-4 lysates at up to 1ug/ml.
Target Reference:
* Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD.; Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome.; Nat Genet. 2001 Nov;29(3):301-5.; Pubmed 11687797

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