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Goat Anti-CENTD3 / ARAP3 Antibody (OAEB02491)

100 ug
$299.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clonality:
Polyclonal
Host:
Goat
Application:
WB, IP
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Gene Symbol:
CENTD3
NCBI Gene Id:
64411
Protein Name:
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Swissprot Id:
Q8WWN8
Protein Accession #:
NP_071926.4
Alias Symbols:
CENTD3, centaurin, delta 3, ARAP3, FLJ21065, ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3, PtdIns(3,4,5)P3-binding protein, phosphoinositide binding protein, ArfGAP with RhoGAP domain, ankyrin repeat and PH d
Replacement Item:
This antibody may replace item sc-61988 from Santa Cruz Biotechnology.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CENTD3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CENTD3.
Predicted Homology Based on Immunogen Sequence:
Human
Complete computational species homology data:
CENTD3 Antibody (OAEB02491)
Peptide Sequence:
CTSSPPSSQPLT
Datasheets/Manuals:
Printable datasheet for anti-CENTD3 antibody - OAEB02491
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:4000.
Western Blot: Preliminary experiments gave no signal but low background in Human Heart and Jurkat extracts at up to 1ug/ml.
This antibody has been successfully used in both Western Blot and Immunoprecipitation on scirrhous human gastric cancer cell lines as descirbed in referred paper.
Target Reference:
* Krugmann S, Anderson KE, Ridley SH, Risso N, McGregor A, Coadwell J, Davidson K, Eguinoa A, Ellson CD, Lipp P, Manifava M, Ktistakis N, Painter G, Thuring JW, Cooper MA, Lim ZY, Holmes AB, Dove SK, Michell RH, Grewal A, Nazarian A, Erdjument-Bromage H, Tempst P, Stephens LR, Hawkins PT.; Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices.; Mol Cell. 2002 Jan;9(1):95-108.; Pubmed 11804589

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