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Goat Anti-BIM (AD / ACD / ABCD isoforms) Antibody (OAEB01291)

100 ug
In Stock
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Predicted Species Reactivity:
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Additional Information:
Reactivity Info: Tested: Human; Expected: Human
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Gene Symbol:
NCBI Gene Id:
Protein Name:
Bcl-2-like protein 11
Swissprot Id:
Protein Accession #:
Alias Symbols:
BIM, BCL2L11, BAM, BOD, BCL2-like 11 (apoptosis facilitator), bcl-2 interacting protein Bim, bcl-2-related ovarian death agonist, bcl-2 interacting mediator of cell death, BIM-alpha6, BIM-beta6, BIM-beta7, BimEL, BimL, OTTHUMP00000197013
Replacement Item:
This antibody may replace item sc-11425 from Santa Cruz Biotechnology.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BCL2L11.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BCL2L11.
This antibody is expected to recognise 3 reported isoforms: BimAD, BimACD, and BimABCD
Predicted Homology Based on Immunogen Sequence:
Human: 100%
Complete computational species homology data:
BCL2L11 Antibody (OAEB01291)
Peptide Sequence:
Printable datasheet for anti-BCL2L11 antibody - OAEB01291
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:16000.
Western Blot: Approx 23kDa band observed in K562 lysates (predicted MW of 19, 9, 12kDa according to NP_619528; NP_996886; NP_619529). Recommended for use at 0.5-2ug/ml.
Target Reference:
* Jiang CC, Lucas K, Avery-Kiejda KA, Wade M, deBock CE, Thorne RF, Allen J, Hersey P, Zhang XD.; Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress.; Cancer Res. 2008 Aug 15;68(16):6708-17.; Pubmed 18701495
* Marani M, Tenev T, Hancock D, Downward J, Lemoine NR.; Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis.; Mol Cell Biol. 2002 Jun;22(11):3577-89.; Pubmed 11997495

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