Size:100 ug
$299.00
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SKU
OAEB02455
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Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)

Catalog#: OAEB02455
Domestic: within 1 week delivery | International: 1 week
This product is Genway GWB-49EE5F
More Information
Predicted Species Reactivity Human, Rat
Product Format Liquid. Tris saline, pH7.3 with 0.02% sodium azide and 0.5% bovine serum albumin.
Clonality Polyclonal
Host Goat
Application IHC-P, P-WB, IF
Reconstitution and Storage Aliquot and store at -20C. Minimize freezing and thawing.
Replacement Item This antibody may replace item sc-20768 from Santa Cruz Biotechnology.
Immunogen Peptide with sequence CNGQPSTLTIFETAL, from the C Terminus of the protein sequence according to NP_005836.2.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Predicted Homology Based on Immunogen Sequence Human, Mouse, Rat
Complete computational species homology data ABCC4 Antibody (OAEB02455)
Peptide Sequence CNGQPSTLTIFETAL
Concentration 0.5 mg/ml
Datasheets/Manuals Printable datasheet for anti-ABCC4 antibody - OAEB02455
Specificity This antibody is expected to recognize isoform 1 (NP_005836.2) only.
Application Info P-ELISA 1:32000
WB 1.0~3.0 ug/ml, 170 kDa band observed in rat renal cortex membranes.
IHC 2.0~4.0 ug/ml. Shows strong cytoplasmic staining in small flat basal cells and weak cytoplasmic staining in the columnar secretory cells of the epithelium.
IF Used successfully in human primary hepatocytes as describied in Xu et al, Am J Physiol Gastrointest Liver Physiol. 2010 Jul;200(1):G126-35, PMID: 20395535.
Target Reference * Schuetz JD, Connelly MC, Sun D, Paibir SG, Flynn PM, Srinivas RV, Kumar A, Fridland A.; MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs.; Nat Med. 1999 Sep;5(9):1048-51.; Pubmed 10470083
Publications

Gori, I. et al. Augmented epithelial multidrug resistance-associated protein 4 expression in peritoneal endometriosis: regulation by lipoxin A(4). Fertil. Steril. 99, 1965-73.e2 (2013). IHC-P, P-ELISA, WB, IF, Human, Rat 23472950

Montani, M. et al. Multidrug resistance protein 4 (MRP4) expression in prostate cancer is associated with androgen signaling and decreases with tumor progression. Virchows Arch. 462, 437-43 (2013). IHC-P, P-ELISA, WB, IF, Human, Rat 23503867

Weerachayaphorn, J. et al. Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 302, G925-36 (2012). IHC-P, P-ELISA, WB, IF, Human, Rat 22345550

Xu, S., Weerachayaphorn, J., Cai, S.-Y., Soroka, C. J. & Boyer, J. L. Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression. Am. J. Physiol. Gastrointest. Liver Physiol. 299, G126-35 (2010). IHC-P, P-ELISA, WB, IF, Human, Rat 20395535

Gene Symbol ABCC4
Alias Symbols ABCC4, MRP4, MOATB, MOAT-B, EST170205, ATP-binding cassette, sub-family C (CFTR/MRP), member 4, canalicular multispecific organic anion transporter (ABC superfamily), Multidrug Resistance Protein 4, RP11-74A12.1, ATP-binding cassette, sub-family
NCBI Gene Id 10257
Protein Name Multidrug resistance-associated protein 4
Swissprot Id O15439
Protein Accession # NP_005836.2
Molecular Weight 150 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ABCC4.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ABCC4.
  1. What is the species homology for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Rat".

  2. How long will it take to receive "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)" provided in?

    This item is provided in "Liquid. Tris saline, pH7.3 with 0.02% sodium azide and 0.5% bovine serum albumin.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    This target may also be called "ABCC4, MRP4, MOATB, MOAT-B, EST170205, ATP-binding cassette, sub-family C (CFTR/MRP), member 4, canalicular multispecific organic anion transporter (ABC superfamily), Multidrug Resistance Protein 4, RP11-74A12.1, ATP-binding cassette, sub-family " in publications.

  5. What is the shipping cost for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "150 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ABCC4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ABCC4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ABCC4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ABCC4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ABCC4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ABCC4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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