Size:400ul
$329.00
In stock
SKU
OAAB09358
Request Bulk
Order Quote
Aviva's
Satisfaction
Guarantee
Contact Us:
  • Toll Free: (888)880-0001
  • Phone: (858)552-6979
  • Email: info@avivasysbio.com
Shipping Info:
  • $40: Antibody & Protein in US
  • $50: 1-2 Kits in US
  • Contact us for international orders.

GNAS Antibody - C-terminal region (OAAB09358)

Catalog#: OAAB09358
Domestic: within 1 week delivery International: 1 week
More Information
Predicted Species Reactivity Human
Product Format Liquid PBS with 0.09% (W/V) sodium azide.
Clonality Polyclonal
Isotype Rabbit IgG
Host Rabbit
Application WB, IHC-P, IF, FC
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-135914 from Santa Cruz Biotechnology.
Immunogen This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human GNAS.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Predicted Homology Based on Immunogen Sequence Mouse, Rat, Bovine, Hamster, Pig
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals Printable datasheet for OAAB09358
Application Info WB: 1:1000
IHC-P: 1:10~50
IF: 1:10~50
FC: 1:10~50
Alias Symbols GNAS
Protein Name GNAS complex locus EMBL AAH89157.2
Description of Target Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
Swissprot Id Q5FWY2
Molecular Weight 44 kDa
Write Your Own Review
You're reviewing:GNAS Antibody - C-terminal region (OAAB09358)
Your Rating