Size:400ul
$329.00
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SKU
OAAB09358
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GNAS Antibody - C-terminal region (OAAB09358)

Catalog#: OAAB09358
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human
Product Format Liquid PBS with 0.09% (W/V) sodium azide.
Clonality Polyclonal
Isotype Rabbit IgG
Host Rabbit
Application WB, IHC-P, IF, FC
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-135914 from Santa Cruz Biotechnology.
Immunogen This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human GNAS.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Predicted Homology Based on Immunogen Sequence Mouse, Rat, Bovine, Hamster, Pig
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals Printable datasheet for OAAB09358
Application Info WB: 1:1000
IHC-P: 1:10~50
IF: 1:10~50
FC: 1:10~50
Alias Symbols GNAS
Protein Name GNAS complex locus EMBL AAH89157.2
Description of Target Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
Swissprot Id Q5FWY2
Molecular Weight 44 kDa
  1. What is the species homology for "GNAS Antibody - C-terminal region (OAAB09358)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "GNAS Antibody - C-terminal region (OAAB09358)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "GNAS Antibody - C-terminal region (OAAB09358)" provided in?

    This item is provided in "Liquid PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GNAS Antibody - C-terminal region (OAAB09358)"?

    This target may also be called "GNAS" in publications.

  5. What is the shipping cost for "GNAS Antibody - C-terminal region (OAAB09358)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GNAS Antibody - C-terminal region (OAAB09358)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GNAS Antibody - C-terminal region (OAAB09358)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "44 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GNAS Antibody - C-terminal region (OAAB09358)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for ""?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for ""?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with ""?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with ""?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with ""?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with ""?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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