GM2A Recombinant Protein (OPCD03602)

Catalog No: OPCD03602

GM2A Recombinant Protein (OPCD03602) using SDS-PAGE

GM2A Recombinant Protein (OPCD03602) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: His24-Ile193
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: GM2A
• Gene Full Name: GM2 ganglioside activator
• Alias Symbols: cerebroside sulfate activator protein;ganglioside GM2 activator;GM2-AP;SAP-3;shingolipid activator protein 3;sphingolipid activator protein 3.
• NCBI Gene Id: 2760
• Protein Name: Ganglioside GM2 activator
• Description of Target: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
• Uniprot ID: P17900
• Protein Accession #: NP_000396.2
• Nucleotide Accession #: NM_000405.4
• Protein Size (# AA): His24~Ile193
• Molecular Weight: 24kDa