Aviva Systems Biology will be closed in observance of Good Friday 3/29/2024. If you are in need of any assistance please email info@avivasysbio.com

Catalog No: OASE00288-HRP
Size:100ug
Price: $429.00
SKU
OASE00288-HRP
Availability: Domestic: within 3-5 days delivery | International: 3-5 days
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.

GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)

Datasheets/ManualsPrintable datasheet for OASE00288-HRP
Product Info
Predicted Species ReactivityMouse, Rat
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityMonoclonal
CloneS355-1
IsotypeIgG1
HostMouse
ConjugationHRP: Horseradish Peroxidase
ApplicationWB, ICC, IHC
Additional InformationBackground Info: Detects ~100kDa. Does not cross-react with GluR2.
::Scientific Background: Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).
::Certificate of Analysis: 1ug/mL was sufficient for detection of GluA1/GluR1 in 20ug of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenFusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1, accession number P19490
PurificationProtein G Purified
Concentration0.6-0.7 mg/ml
Dilution1:1000 WB
Storage BufferPBS pH 7.4, 50% glycerol, 0.1% sodium azide
Reference1. Potier M.C., Spillantini M.G., Carter N.P. (1992) DNA Seq. 2(4): 211-218.
2. Puckett, C., et al. (1991) Proc. Nat. Acad. Sci. USA 88(17): 7557-7561.
3. Gregor, P., et al. (1993) Proc. Nat. Acad. Sci. USA 90: 3053-3057.
Gene SymbolGria1
Gene Full Nameglutamate receptor, ionotropic, AMPA 1
Alias SymbolsGluA1, gluR-A
NCBI Gene Id50592
Uniprot IDP19490
Protein Accession #NP_113796
  1. What is the species homology for "GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat".

  2. How long will it take to receive "GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)"?

    This target may also be called "GluA1, gluR-A" in publications.

  5. What is the shipping cost for "GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GRIA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GRIA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GRIA1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GRIA1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GRIA1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GRIA1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:GluA1/GluR1 Glutamate Receptor Antibody : HRP (OASE00288-HRP)
Your Rating
We found other products you might like!