GLRX1 Yeast Protein (OPPA01680)

Catalog No: OPPA01680 (Formerly GWB-330B76)

Size:10UG

Product Info

• Predicted Species Reactivity: Yeast
• Product Format: Glutaredoxin solution contains 25mM Tris-HCl pH-7.5 & 0.01% Na Azide. Physical appearance: Sterile Filtered clear colorless solution.
• Host: E. Coli
• Application: ELISA, WB
  Product Introduction: GLRX1 has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase. reduces low molecular weight disulfides and proteins. Glutaredoxin is a glutathione (GSH)-dependent hydrogen donor for ribonucleotide reductase and also catalyzes glutathione-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. GLRX1 is multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage.
  Product Description: Glutaredoxin Saccharamyces cerevisiae Recombinant conaining 6x His tag at C-Terminus produced in E.Coli is a single, non-glycosylated, Polypeptide chain having a molecular mass of 16 kDa.
• Reconstitution and Storage: 1 week at 2-10C. For long term store at -20 to -80C.
• Purity: Greater than 90% as determined by SDS-PAGE.
• Application Info: ELISA, Western Blot, strongly binds to glutathione, reduced and oxidized.

Target Info

• Gene Symbol: GLRX1 Yeast
• Alias Symbols: Thioltransferase, GRX, GLRX1, GRX1, GRX-1, GLRX-1, Glutathione-dependent oxidoreductase 1, Glutaredoxin 1, GLRX1 Yeast, Glutaredoxin 1 Yeast Recombinant
• NCBI Gene Id: 850322
• Protein Name: Glutaredoxin-1
• Description of Target: Recombinant Yeast Glutaredoxin 1
• Uniprot ID: P25373
• Protein Accession #: NP_009895.1
• Protein Size (# AA): Recombinant