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Catalog No: OPPA02149 (Formerly GWB-625A6F)
Size:10UG
Price: $75.00
SKU
OPPA02149
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GLO1 Protein (OPPA02149)

Datasheets/ManualsPrintable datasheet for OPPA02149
Product Info
Predicted Species ReactivityHuman
Product FormatGlyoxalase-1 solution containing 20mM Tris pH-8, 1mM DTT and 10% glycerol. Physical appearance: Sterile filtered colorless solution.
HostE. Coli
::Product Introduction: GLO1 is involved in the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. GLO1 is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. GLO1 enzyme is ubundantly expressed and present in numerous tumor cell lines, in which its concentration is often upregulated ubiquitisly. GLO1 is a major susceptible gene for autism in an ethnic Chinese population from Taiwan. GLO1 might be involved in the pathophysiology of mood disorders. GLO1 plays a role in the pathophysiology of mood disorders. Overexpression of GLO1 is associated with kidney tumor.
Product Description: Glyoxalase-I Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 184 amino acids and having a molecular mass of 20.7 kDa. Glyoxalase-1 is purified by proprietary chromatographic techniques.
Reconstitution and StorageGlyoxalase-I Human Recombinant although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
PurityGreater than 90.0% as determined by SDS-PAGE.
Peptide SequenceMAEPQPPSGG LTDEAALSCC SDADPSTKDF LLQQTMLRVK DPKKSLDFYT RVLGMTLIQK CDFPIMKFSL YFLAYEDKND IPKEKDEKIAWALSRKATLE LTHNWGTEDD ETQSYHNGNS DPRGFGHIGI AVPDVYSACK RFEELGVKFV KKPDDGKMKG LAFIQDPDGY WIEILNPNKM ATLM.
Gene SymbolGLO1
Alias SymbolsGLYI, GLOD1, HEL-S-74
NCBI Gene Id2739
Protein NameLactoylglutathione lyase
Description of TargetRecombinant Human Glyoxalase-I
Uniprot IDQ04760
Protein Accession #NP_006699.2
Protein Size (# AA)Recombinant
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