Size:100 ul
Special Price $229.00 Regular Price $319.00
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SKU
ARP31885_P050
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Conjugation Options

ARP31885_P050-FITC Conjugated

ARP31885_P050-HRP Conjugated

ARP31885_P050-Biotin Conjugated

More Information
Tested Species Reactivity Human, Mouse
Predicted Species Reactivity Human
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-20290 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human GLI2
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Human: 100%
Complete computational species homology data Anti-GLI2 (ARP31885_P050)
Peptide Sequence Synthetic peptide located within the following region: RNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTE
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-GLI2 (ARP31885_P050) antibody is Catalog # AAP31885 (Previous Catalog # AAPP02680)
Datasheets/Manuals Printable datasheet for anti-GLI2 (ARP31885_P050) antibody
Target Reference Ikram,M.S., et al., (2004) J. Invest. Dermatol. 122 (6), 1503-1509
Publications

Enzenhofer, E; Parzefall, T; Haymerle, G; Schneider, S; Kadletz, L; Heiduschka, G; Pammer, J; Oberndorfer, F; Wrba, F; Loader, B; Grasl, MC; Perisanidis, C; Erovic, BM; Impact of Sonic Hedgehog Pathway Expression on Outcome in HPV Negative Head and Neck Carcinoma Patients after Surgery and Adjuvant Radiotherapy. 11, e0167665 (2016). IHC, WB, Human 27918595

Gene Symbol GLI2
Official Gene Full Name GLI family zinc finger 2
Alias Symbols HPE9, THP1, THP2
NCBI Gene Id 2736
Protein Name Zinc finger protein GLI2
Description of Target GLI2 encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
Swissprot Id P10070
Protein Accession # NP_084655
Nucleotide Accession # NM_030379
Protein Size (# AA) 1258
Molecular Weight 133kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express GLI2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express GLI2.
Protein Interactions SPOP; SKI; HDAC1; STK36; FBXW11; SUFU; ZIC2; ZIC1; CREB1; TBP;
  1. What is the species homology for "GLI2 Antibody - middle region (ARP31885_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "GLI2 Antibody - middle region (ARP31885_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "GLI2 Antibody - middle region (ARP31885_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GLI2 Antibody - middle region (ARP31885_P050)"?

    This target may also be called "HPE9, THP1, THP2" in publications.

  5. What is the shipping cost for "GLI2 Antibody - middle region (ARP31885_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GLI2 Antibody - middle region (ARP31885_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GLI2 Antibody - middle region (ARP31885_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "133kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GLI2 Antibody - middle region (ARP31885_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "GLI2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GLI2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GLI2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GLI2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GLI2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GLI2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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