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Datasheets/Manuals | Printable datasheet for OAAB11368 |
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Predicted Species Reactivity | Human, Mouse, Cow, Sheep |
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Product Format | Liquid. PBS with 0.09% (W/V) sodium azide. |
Clonality | Polyclonal |
Isotype | Ig |
Host | Rabbit |
Application | WB, IHC-P |
Additional Information | Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Cellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction |
Reconstitution and Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | This GJB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-226 amino acids from the C-terminal region of human GJB2. |
Purification | This antibody is purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Concentration | 2 mg/ml |
Intended Use | For research use only and not for use in diagnostic or therapeutic procedures. |
Application Info | WB: 1:1000 IHC-P: 1:50~100 Optimal dilutions should be determined by the end user. |
Gene Symbol | GJB2 |
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Alias Symbols | HID, KID, PPK, BAPS, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A |
NCBI Gene Id | 2706 |
Protein Name | Gap junction beta-2 protein |
Description of Target | Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Immunohistochemical staining of human cochlear cells demonstrated high levels of GJB2 expression. Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness. |
Uniprot ID | P29033 |
Protein Accession # | NP_003995.2 |
Molecular Weight | 26 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "GJB2 Antibody - C-terminal region (OAAB11368)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Cow, Sheep".
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How long will it take to receive "GJB2 Antibody - C-terminal region (OAAB11368)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "GJB2 Antibody - C-terminal region (OAAB11368)" provided in?
This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "GJB2 Antibody - C-terminal region (OAAB11368)"?
This target may also be called "HID, KID, PPK, BAPS, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A" in publications.
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What is the shipping cost for "GJB2 Antibody - C-terminal region (OAAB11368)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "GJB2 Antibody - C-terminal region (OAAB11368)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "GJB2 Antibody - C-terminal region (OAAB11368)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "26 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "GJB2 Antibody - C-terminal region (OAAB11368)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "GJB2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "GJB2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "GJB2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "GJB2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "GJB2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "GJB2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.