GJA1 Recombinant Protein (OPCD02580)

Catalog No: OPCD02580

GJA1 Recombinant Protein (OPCD02580) using SDS-PAGE

GJA1 Recombinant Protein (OPCD02580) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser180-Ile382
  Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junctio
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Gja1
• Gene Full Name: gap junction protein, alpha 1
• Alias Symbols: alpha 1 connexin;AU042049;AW546267;Cnx4;Cnx43;conne;connexin k1;connexin43;connexin-43;Cx43;Cx43al;Cx43alpha1;Cxnk1;gap junction 43 kDa heart protein;gap junction alpha-1 protein;gap junction membrane channel protein alpha 1;Gja-;Gja-1;Npm1.
• NCBI Gene Id: 14609
• Protein Name: Gap junction alpha-1 protein
• Description of Target: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibition through the regulation of NOV expression and localization (PubMed:15181016). Plays an essential role in gap junction communication in the ventricles (PubMed:26403541).
• Uniprot ID: P23242
• Protein Accession #: NP_034418.1
• Nucleotide Accession #: NM_010288.3
• Protein Size (# AA): Ser180~Ile382
• Molecular Weight: 26kDa