GJA1 Recombinant Protein (OPCD02578)

Catalog No: OPCD02578

GJA1 Recombinant Protein (OPCD02578) using SDS-PAGE

GJA1 Recombinant Protein (OPCD02578) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser180-Ile382
  Subcellular Location: Membrane
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: GJA1
• Gene Full Name: gap junction protein alpha 1
• Alias Symbols: AVSD3;CMDR;connexin-43;CX43;EKVP;EKVP3;gap junction 43 kDa heart protein;gap junction alpha-1 protein;gap junction protein, alpha 1, 43kDa;GJAL;HLHS1;HSS;ODDD;PPKCA.
• NCBI Gene Id: 2697
• Protein Name: Gap junction alpha-1 protein
• Description of Target: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).
• Uniprot ID: P17302
• Protein Accession #: NP_000156.1
• Nucleotide Accession #: NM_000165.4
• Protein Size (# AA): Ser244~Ile382
• Molecular Weight: 26kDa