GH1 Antibody (OOPA00064)

Catalog No: OOPA00064

Size:2UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Sterile Filtered White lyophilized (freeze-dried) powder.
• Clonality: Monoclonal
• Host: Nicotiana benthamiana plant
• Additional Information: Solubility: It is recommended to Reconstitution: Reconstitute the lyophilized GH in sterile 18M-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
  Product Introduction: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
  Product Description: GH human Recombinant produced in Nicotiana benthamiana plant is a single chain containing 205 amino acids (molecular formula C1025H1570N280O306S7) and 6-His-tag at the N-terminal having the total molecular mass of 22.9kDa.
• Reconstitution and Storage: Lyophilized GH although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution GH should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purification: Greater than 97.0% as determined by Analysis by SDS-PAGE.
• Peptide Sequence: HHHHHHFPTI PLSRPFDNAM LRAHRLHQLA FDTYQEFEEA YIPKEQKYSF LQNPQTSLCF SESIPTPSNR EETQQKSNLE LLRISLLLIQ SWLEPVQFLR SVFANSLVYG ASDSNVYDLL KDLEEGIQTL MGRLEDGSPR TGQIFKQTYS KFDTNSHNDD ALLKNYGLLY CFRKDMDKVE TFLRIVQCRS VEGSCGFAG
• Formulation: Lyophilized from 1mg/ml solution in PBS 0.05M buffer at pH 7.5.
• Purity: Greater than 97.0% as determined by Analysis by SDS-PAGE.
• Biological Activity: The biological activity of human Growth Hormone is measured by cell proliferation using Nb2-11 cells. ED50 < 0.04-0.1 ng/mL.

Target Info

• Gene Symbol: GH1
• Gene Full Name: Somatotropin
• Alias Symbols: GH, GHN, GH-N, GHB5, IGHD2, hGH-N, IGHD1A, IGHD1B
• NCBI Gene Id: 2688
• Protein Name: Somatotropin
• Uniprot ID: P01241
• Protein Accession #: NP_000506.2; NP_072053.1; NP_072054.1
• Nucleotide Accession #: NM_000515.4; NM_022559.3; NM_022560.3
• Protein Size (# AA): Recombinant