GEMIN8 Antibody (OACA06159)

Catalog No: OACA06159

Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution of 1:100

Western Blot
Positive WB detected in: HepG2 whole cell lysate,HEK293 whole cell lysate,Mouse kidney tissue
All lanes: GEMIN8 antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/5,0000 dilution
Predicted band size: 29 kDa
Observed band size: 29,33 kDa

Western Blot
Positive WB detected in: HepG2 whole cell lysate,HEK293 whole cell lysate,Mouse kidney tissue
All lanes: GEMIN8 antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/5,0000 dilution
Predicted band size: 29 kDa
Observed band size: 29,33 kDa

Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution of 1:100

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human Gem-associated protein 8 protein (1-242AA)
• Purification: Protein G Purified
• Preservative: 0.03% Proclin 300
• Formulation: 50% Glycerol, 0.01M PBS, PH 7.4

Target Info

• Gene Symbol: GEMIN8
• Gene Full Name: gem nuclear organelle associated protein 8
• Alias Symbols: FAM51A1;family with sequence similarity 51, member A1;gem-associated protein 8;gemin-8;Protein FAM51A1.
• NCBI Gene Id: 54960
• Protein Name: Gem-associated protein 8
• Description of Target: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
• Uniprot ID: Q9NWZ8
• Protein Accession #: NP_001035944
• Nucleotide Accession #: NM_001042479