Gemcitabine HCl (OOMC00034)

Catalog No: OOMC00034

Product Info

• Product Format: Powder
• Additional Information: CAS: 122111-03-9
  Molecular Formula: C9H11F2N3O4 - HCl
  Chemical Name: 2’-Deoxy-2’,2’-difluorocytidine hydrochloride
  Primary Activity: Nucleoside analog
  COVID-19 Rationale: Inhibits SARS-CoV and MERS-CoV in cells
• Reconstitution and Storage: Soluble in DMSO (up to 20 mg/ml) or in Water (up to 25 mg/ml). Store at -20C.
• Purity: > 98%
• Reference: 1) Mini et al. (2006), Cellular Pharmacology of Gemcitabine; Ann.Oncol. 17 v7 2) Heinemann et al. (1995), Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism; Semin.Oncol. 22 11 3) Heinemann et al. (1992), Cellular elimination of 2’,2’-difluorodeoxycytidine 5’triphosphate: a mechanism of self-potentiation; Cancer Res. 52 533 4) Pourquier et al. (2002), Gemcitabine (2’,2’-difluoro-2’-deoxycytidine), an antimetabolite that poisons topoisomerase I; Clin.Cancer Res. 8 2499

Target Info

• Alias Symbols: dFdC
• Molecular Weight: 299.66 g/mol