GCKR Recombinant Protein (OPCD03562)

Catalog No: OPCD03562

GCKR Recombinant Protein (OPCD03562) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Ctrl (+), SDS-PAGE, WB
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Val90-Ala286
  Subcellular Location: Nucleus. Cytoplasm
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Gckr
• Gene Full Name: glucokinase regulator
• Alias Symbols: GLRE;glucokinase (hexokinase 4) regulator;glucokinase regulatory protein.
• NCBI Gene Id: 25658
• Protein Name: Glucokinase regulatory protein
• Description of Target: Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
• Uniprot ID: Q07071
• Protein Accession #: NP_037252.1
• Nucleotide Accession #: NM_013120.2
• Protein Size (# AA): Val90~Val286
• Molecular Weight: 22kDa