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Catalog No: OPCD03560
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OPCD03560
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Datasheets/ManualsPrintable datasheet for GCKR Recombinant Protein (OPCD03560)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Gly17-Lys261
::Subcellular Location: Cytoplasm. Nucleus.
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolGckr
Gene Full Nameglucokinase regulatory protein
Alias SymbolsGK;GKRP;glucokinase regulator;glucokinase regulatory protein.
NCBI Gene Id231103
Protein NameGlucokinase regulatory protein
Description of TargetInhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (By similarity).
Uniprot IDQ91X44
Protein Accession #NP_659158.1
Nucleotide Accession #NM_144909.1
Protein Size (# AA)Gly17~Lys261
Molecular Weight30.2kDa
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