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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for GCK Antibody (OACA07292) (OACA07292) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Glucokinase protein (1-300AA) |
| Purification | Affinity Purified |
| Preservative | 0.02% sodium azide |
| Formulation | PBS with, 50% glycerol, pH7.3. |
| Reference | [1]"The previously reported T342P GCK missense variant is not a pathogenic mutation causing MODY."Steele A.M., Tribble N.D., Caswell R., Wensley K.J., Hattersley A.T., Gloyn A.L., Ellard S.Diabetologia 54:2202-2205(2010). [2]"Neonatal diabetes mellitus due to complete glucokinase deficiency." Njoelstad P.R., Soevik O., Cuesta-Munoz A., Bjoerkhaug L., Massa O., Barbetti F., Undlien D.E., Shiota C., Magnuson M.A., Molven A., Matschinsky F.M., Bell G.I.N. Engl. J. Med. 344:1588-1592(2000). [4]"Identification of glucokinase mutation in subjects with post-renal transplantation diabetes mellitus."Nam J.H., Lee H.C., Kim Y.H., Cha B.S., Song Y.D., Lim S.K., Kim K.R., Huh K.B.Diabetes Res. Clin. Pract. 50:169-176(1999). |
| Gene Symbol | GCK |
|---|---|
| Gene Full Name | glucokinase |
| Alias Symbols | ATP:D-hexose 6-phosphotransferase;FGQTL3;GK;GLK;glucokinase (hexokinase 4);hexokinase D, pancreatic isozyme;hexokinase type IV;hexokinase-4;Hexokinase-D;HHF3;HK IV;HK4;HKIV;HXKP;LGLK;MODY2;PNDM1. |
| NCBI Gene Id | 2645 |
| Protein Name | Glucokinase |
| Description of Target | Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage. |
| Uniprot ID | P35557 |
| Protein Accession # | NP_000153 |
| Nucleotide Accession # | NM_000162 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "GCK Antibody (OACA07292)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "GCK Antibody (OACA07292)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "GCK Antibody (OACA07292)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "GCK Antibody (OACA07292)"?
This target may also be called "ATP:D-hexose 6-phosphotransferase;FGQTL3;GK;GLK;glucokinase (hexokinase 4);hexokinase D, pancreatic isozyme;hexokinase type IV;hexokinase-4;Hexokinase-D;HHF3;HK IV;HK4;HKIV;HXKP;LGLK;MODY2;PNDM1." in publications.
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What is the shipping cost for "GCK Antibody (OACA07292)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "GCK Antibody (OACA07292)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "GCK Antibody (OACA07292)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "GCK Antibody (OACA07292)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "GCK"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "GCK"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "GCK"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "GCK"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "GCK"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "GCK"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
