GCAP1 Antibody - C-terminal region (OAAB11389)

Catalog No: OAAB11389

Size:400ul

The anti-GCAP1 C-term Pab (Cat. #OAAB11389) is used in Western blot to detect GCAP1 in Y79 cell lysate.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Product Info

• Predicted Species Reactivity: Human, Cow
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: IHC-P, WB
• Additional Information: Precautions: GCAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure
  Cellular Location: Membrane; Lipid-anchor.
  Tissue Location: Retina; cone outer and inner segments, in particular, in disk membrane regions, and to a lesser extent rod inner and outer segments
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This GCAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-191 amino acids from the C-terminal region of human GCAP1.
• Predicted Homology Based on Immunogen Sequence: Cow; Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: GUCA1A
• Alias Symbols: COD3, GCAP, GUCA, GCAP1, GUCA1, CORD14, C6orf131
• NCBI Gene Id: 2978
• Protein Name: Guanylyl cyclase-activating protein 1
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P43080
• Protein Accession #: NP_000400.2
• Molecular Weight: 22920 Da