GARS Recombinant Protein (OPCD03438)

Catalog No: OPCD03438

GARS Recombinant Protein (OPCD03438) using SDS-PAGE

GARS Recombinant Protein (OPCD03438) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Val567-Glu735
  Subcellular Location: Mitochondrion, Cytoplasm
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: GARS1
• Gene Full Name: glycyl-tRNA synthetase 1
• Alias Symbols: ap4A synthetase;AP-4-A synthetase;Charcot-Marie-Tooth neuropathy 2D;Charcot-Marie-Tooth neuropathy, neuronal type, D;CMT2D;diadenosine tetraphosphate synthetase;DSMAV;GARS;glycine--tRNA ligase;Glycyl-tRNA synthetase;Glycyl-tRNA synthetase 1;GlyRS;HMN5;HMN5A;SMAD1;SMAJI.
• NCBI Gene Id: 2617
• Protein Name: Glycine--tRNA ligase
• Description of Target: Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP) (PubMed:17544401, PubMed:28675565, PubMed:24898252). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis (PubMed:19710017).
• Uniprot ID: P41250
• Protein Accession #: NP_001303701.1
• Nucleotide Accession #: NM_001316772.1
• Protein Size (# AA): Val567~Glu735
• Molecular Weight: 23kDa