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Catalog No: OAAB17810
Size:100ul
Price: $463.00
SKU
OAAB17810
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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Datasheets/ManualsPrintable datasheet for OAAB17810
Product Info
Predicted Species ReactivityMouse, Rat, Rabbit
Product Format0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
ClonalityMonoclonal
HostMouse
ApplicationWB
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Application InfoWB: 1:1000
ReferenceFort P., et al.Nucleic Acids Res. 13:1431-1442(1985).
Tso J.Y., et al.Nucleic Acids Res. 13:2485-2502(1985).
Tajima H., et al.NeuroReport 10:2029-2033(1999).
Zheng J., et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Lubec G., et al.Submitted (APR-2007) to UniProtKB.
Gene SymbolGAPDH
Alias SymbolsGapd, BARS-38
NCBI Gene Id24383
Description of TargetHas both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation (By similarity).
Uniprot IDP04797
Molecular Weight36 kDa
  1. What is the species homology for "GAPDH Antibody (OAAB17810)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat, Rabbit".

  2. How long will it take to receive "GAPDH Antibody (OAAB17810)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "GAPDH Antibody (OAAB17810)" provided in?

    This item is provided in "0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GAPDH Antibody (OAAB17810)"?

    This target may also be called "Gapd, BARS-38" in publications.

  5. What is the shipping cost for "GAPDH Antibody (OAAB17810)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GAPDH Antibody (OAAB17810)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GAPDH Antibody (OAAB17810)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "36 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GAPDH Antibody (OAAB17810)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GAPDH"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GAPDH"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GAPDH"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GAPDH"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GAPDH"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GAPDH"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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