Size:100 ul
$185.00
In Stock
SKU
OAAH00016
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More Information
Predicted Species Reactivity Human, Rat, Mouse, Monkey, Dog, Chinese hamster
Clonality Monoclonal
Isotype Mouse IgG1
Host Mouse
Application WB
Reconstitution and Storage Store the product at -20C. Stable for one year from the date of shipment.
Replacement Item This antibody may replace item sc-113612 from Santa Cruz Biotechnology.
Immunogen This Aviva monoclonal antibody is produced by immunizing animals with a synthetic peptide (KLH-coupled) of human GAPDH.
Datasheets/Manuals Printable datasheet for GAPDH (2A8) mAb (OAAH00016) OAAH00016
Specificity GAPDH (2A8) Mouse mAb detects endogenous levels of total GAPDH protein.
Source Mouse mAb
Application Info WB: 1: 2000-1:5000
Target Reference 1. Barber, R.D. et al. 2005. GAPDH as a housekeeping gene: analysis of
GAPDH mRNA expression in a panel of 72 human tissues. Physiol.
Genomics 21, 389-95.
2. Hara, M.R. and Snyder, S.H. 2006. Nitric oxide-GAPDH-Siah: a novel cell
death cascade. Cell Mol. Neurobiol. 26, 527-38.
3. Zheng, L. et al. 2003. S phase activation of the histone H2B promoter by
OCA-S, a coactivator complex that contains GAPDH as a key component.
Cell 114, 255-66.
4. Bae, B.I. et al. 2006. Mutant huntingtin: nuclear translocation and
cytotoxicity mediated by GAPDH. Proc. Natl. Acad. Sci. USA 103, 3405-9.
5. Wang, Q. et al. 2005. Proteomic analysis of neurofibrillary tangles in
Alzheimer disease identifies GAPDH as a detergent-insoluble paired
helical filament tau binding protein. FASEB J. 19, 869-71.
Gene Symbol GAPDH
Alias Symbols G3PD, GAPD, HEL-S-162eP,
NCBI Gene Id 2597
Protein Name Glyceraldehyde-3-phosphate dehydrogenase
Description of Target Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the phosphorylation of glyceraldehyde-3-phosphate during glycolysis. Though differentially expressed from tissue to tissue, GAPDH is thought to be a constitutively expressed housekeeping protein. For this reason, GAPDH mRNA and protein levels are often measured as controls in experiments quantifying specific changes in expression of other targets. Recent work has elucidated roles for GAPDH in apoptosis, gene expression and nuclear transport. GAPDH may also play a role in neurodegenerative pathologies such as Huntington and Alzheimer's diseases.
Swissprot Id P04406
Molecular Weight 37 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express GAPDH.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express GAPDH.
  1. What is the species homology for "GAPDH (2A8) mAb (OAAH00016)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Rat, Mouse, Monkey, Dog, Chinese hamster".

  2. How long will it take to receive "GAPDH (2A8) mAb (OAAH00016)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "GAPDH (2A8) mAb (OAAH00016)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GAPDH (2A8) mAb (OAAH00016)"?

    This target may also be called "G3PD, GAPD, HEL-S-162eP, " in publications.

  5. What is the shipping cost for "GAPDH (2A8) mAb (OAAH00016)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GAPDH (2A8) mAb (OAAH00016)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GAPDH (2A8) mAb (OAAH00016)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "37 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GAPDH (2A8) mAb (OAAH00016)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "GAPDH"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GAPDH"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GAPDH"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GAPDH"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GAPDH"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GAPDH"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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