GALECTIN-3 Recombinant Protein (OPSA11036)

Catalog No: OPSA11036 (Formerly GWB-E7CEE0)

Size:50UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Lyophilized. Phosphate buffered saline
• Application: Enzyme-linked immunosorbent assay|Functional assay|Western blot
• Additional Information: Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 ug/ml with a peak response obtained at 250 ug/ml.
  Approx Protein Conc: Total protein concentration 0.1 mg/ml after reconstitution
  Buffer solution: Phosphate buffered saline
  Endotoxin Level: < 1 EU/ug
  Label Protein Molar Ratio: Purified recombinant galectin-3 expressed in E.coli
  Preservative: None present
• Reconstitution and Storage: -20°C
• Predicted Homology Based on Immunogen Sequence: Human
• Purification: Purified recombinant galectin-3 expressed in E.coli
• Concentration: 0.1 mg/ml
• Purity: >98% by SDS PAGE/HPLC analysis
• Specificity: Galectin-3 (Gal-3) is a member of the galectin family of beta-galactoside-binding proteins, which is involved in both intracellular and extracellular functions and exhibits anti-apoptotic properties.
  Gal-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Gal-3 acts as a regulator of tumour metastasis, and several studies have shown a correlation between levels of Gal-3 and tumour progression in liver, thyroid, colon, gastric and breast carcinomas, making Gal-3 an emerging cancer marker.
  
• Application Info: ELISA:    0.2 - 0.4ng/well
  Western Blotting:    1.5 - 3.0ng/lane
  

Target Info

• Gene Symbol: LGALS3
• Alias Symbols: L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2
• NCBI Gene Id: 3958
• Protein Name: Galectin-3
• Description of Target: RECOMBINANT HUMAN GALECTIN-3
  
• Uniprot ID: P17931
• Protein Accession #: NP_002297.2
• Protein Size (# AA): Recombinant
• Molecular Weight: 26.0kD (250 amino acid residues)