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GALECTIN-3 Recombinant Protein (OPSA11036)

50 ug
$459.00
In Stock
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Gene Symbol:
LGALS3
Alias Symbols:
L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2, LGALS3
NCBI Gene Id:
3958
Swissprot Id:
P17931
Protein Accession #:
NP_002297.2
Protein Name:
Galectin-3
Description of Target:
RECOMBINANT HUMAN GALECTIN-3
Protein Size (# AA):
250
Molecular Weight:
26.0kD (250 amino acid residues)
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express LGALS3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express LGALS3.
Product Format:
Purified recombinant protein - lyophilised
Predicted Homology Based on Immunogen Sequence:
Human
Predicted Species Reactivity:
Human
Purity:
>98% by SDS PAGE/HPLC analysis
Specificity:
Galectin-3 (Gal-3) is a member of the galectin family of beta-galactoside-binding proteins, which is involved in both intracellular and extracellular functions and exhibits anti-apoptotic properties.
Gal-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Gal-3 acts as a regulator of tumour metastasis, and several studies have shown a correlation between levels of Gal-3 and tumour progression in liver, thyroid, colon, gastric and breast carcinomas, making Gal-3 an emerging cancer marker.
Application Info:
ELISA:    0.2 - 0.4ng/well
Western Blotting:    1.5 - 3.0ng/lane
Additional Information:
Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 ug/ml with a peak response obtained at 250 ug/ml.
Approx Protein Conc: Total protein concentration 0.1 mg/ml after reconstitution
Buffer solution: Phosphate buffered saline
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Endotoxin Level: < 1 EU/ug
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Label Protein Molar Ratio: Purified recombinant galectin-3 expressed in E.coli
Preservative: None present
Reconstitution and Storage:
Reconstitution: Reconstitute with 0.5ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Aviva Systems Biology recommend that the vial is gently mixed after reconstitution.
Datasheets/Manuals:
Printable datasheet for OPSA11036

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