GADD45GIP1 Antibody (OAAF03716)

Catalog No: OAAF03716

Size:100 ug

Immunohistochemistry analysis of paraffin-embedded human brain, using GADD45GIP1 Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human GADD45GIP1.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: GADD45GIP1 antibody detects endogenous levels of total GADD45GIP1 protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: IHC: 1:50~1:100; ELISA: 1:40000
• Reference: Goernemann J., Virology 303:69-78(2002).
  Chung H.K., J. Biol. Chem. 278:28079-28088(2003).
  The MGC Project Team, Genome Res. 14:2121-2127(2004).

Target Info

• Gene Symbol: GADD45GIP1
• Gene Full Name: GADD45G interacting protein 1
• Alias Symbols: 39S ribosomal protein L59, mitochondrial;CKBBP2;CKbetaBP2;CKII beta binding protein 2;CKII beta-associating protein;CR6 interacting factor 1;CR6-interacting factor 1;CRIF1;growth arrest- and DNA damage-inducible GADD45G-interacting protein;growth arrest and DNA damage-inducible proteins-interacting protein 1;growth arrest and DNA-damage-inducible, gamma interacting protein 1;mitochondrial large ribosomal subunit protein CRIF1;mitochondrial large ribosomal subunit protein mL64;MRP-L59;p53-responsive gene 6 protein;papillomavirus L2 interacting nuclear protein 1;Papillomavirus L2-interacting nuclear protein 1;PLINP;Plinp1;PLINP-1;PRG6.
• NCBI Gene Id: 90480
• Protein Name: Growth arrest and DNA damage-inducible proteins-interacting protein 1
• Description of Target: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
• Uniprot ID: Q8TAE8
• Protein Accession #: NP_443082.2
• Molecular Weight: 25 kDa