Catalog No: ARP35283_P050-Biotin
Size:100ul
Price: $434.00
SKU
ARP35283_P050-Biotin
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GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)

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Datasheets/ManualsPrintable datasheet for anti-GABRQ (ARP35283_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human GABRQ
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 87%; Dog: 87%; Guinea Pig: 80%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: KFHFEFSSAVPEVVLNLFNCKNCANEAVVQKILDRVLSRYDVRLRPNFGG
Concentration0.5 mg/ml
Blocking PeptideFor anti-GABRQ (ARP35283_P050-Biotin) antibody is Catalog # AAP35283 (Previous Catalog # AAPP06521)
Subunittheta
ReferenceSinkkonen,S.T., et al., (2000) J. Neurosci. 20 (10), 3588-3595
Publications

Fatemi, S. H., Folsom, T. D., Rooney, R. J. & Thuras, P. D. mRNA and protein expression for novel GABAA receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl. Psychiatry 3, e271 (2013). WB, Mouse, Rabbit, Rat, Human, Pig, Horse, Bovine, Dog, Guinea pig 23778581

Gene SymbolGABRQ
Gene Full NameGamma-aminobutyric acid (GABA) A receptor, theta
Alias SymbolsTHETA
NCBI Gene Id55879
Protein NameGamma-aminobutyric acid receptor subunit theta
Description of TargetThe gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. GABRQ gene is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases:early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. It is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).
Uniprot IDQ9UN88
Protein Accession #NP_061028
Nucleotide Accession #NM_018558
Protein Size (# AA)632
Molecular Weight72kDa
  1. What is the species homology for "GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)"?

    This target may also be called "THETA" in publications.

  5. What is the shipping cost for "GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "72kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GABRQ Antibody - N-terminal region : Biotin (ARP35283_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GABRQ"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GABRQ"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GABRQ"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GABRQ"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GABRQ"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GABRQ"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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