GABRB3 Antibody (OAPC00272)

Catalog No: OAPC00272

Size:100 uL

Western blot of rat brain lysate showing specific immunolabeling of the ~53 kDa b3-subunit of the GABAA-R.

Immunostaining of mouse retina showing specific labeling of the GABAA b3 subunit in green, calbindin in red and DNA in blue. Photo courtesy of Dr. Arlene Hirano, UCLA.

Product Info

• Predicted Species Reactivity: Mouse, Rat
• Product Format: Liquid. 10mM HEPES (pH 7.5), 150mM NaCl, 100 ug/mL BSA & 50% glycerol. Adequate amount of material to conduct 10-mini Western blots.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: Fusion protein from the cytoplasmic loop of the beta 3-subunit of rat GABAA receptor
• Purification: Affinity purified.
• Concentration: 1 mg/ml
• Application Info: WB: 1:1000
  IHC: 1:300

Target Info

• Gene Symbol: GABRB3
• Gene Full Name: Gamma-aminobutyric acid type A receptor beta 3 subunit
• Alias Symbols: GABA(A) receptor subunit beta-3, Gabrb-3, Gamma-aminobutyric acid receptor subunit beta-3
• NCBI Gene Id: 24922
• Protein Name: Gamma-aminobutyric acid receptor subunit beta-3
• Description of Target: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
• Uniprot ID: P63079
• Protein Accession #: NP_058761
• Nucleotide Accession #: NM_017065
• Molecular Weight: 53 kDa