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GABRB3 Antibody (OAEB00935)

100 ug
$349.00
In Stock
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Gene Symbol:
GABRB3
NCBI Gene Id:
2562
Protein Name:
Gamma-aminobutyric acid receptor subunit beta-3
Swissprot Id:
P28472
Protein Accession #:
NP_000805.1
Alias Symbols:
GABRB3, gamma-aminobutyric acid (GABA) A receptor, beta 3, MGC9051, GABA(A) receptor beta-3 subunit, GABA-A receptor beta-3 subunit, GABA-alpha receptor beta-2 subunit, GABAA receptor beta-3 subunit
Replacement Item:
This antibody may replace item sc-111141 from Santa Cruz Biotechnology.
Host:
Goat
Clonality:
Polyclonal
Application:
IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express GABRB3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express GABRB3.
Immunogen:
This antibody is expected to recognize both reported isoforms (NP_000805.1, NP_068712.1).
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 91%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 91%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
GABRB3 Antibody (OAEB00935)
Peptide Sequence:
C-EKTAKAKNDRSK
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals:
Printable datasheet for anti-GABRB3 antibody - OAEB00935
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:8000.
Western Blot: Preliminary experiments in Human Brain (Cerebral Cortex, Frontal Cortex and Cerebellum) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
Target Reference:
* Tanaka M, Olsen RW, Medina MT, Schwartz E, Alonso ME, Duron RM, Castro-Ortega R, Martinez-Juarez IE, Pascual-Castroviejo I, Machado-Salas J, Silva R, Bailey JN, Bai D, Ochoa A, Jara-Prado A, Pineda G, Macdonald RL, Delgado-Escueta AV.; Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy.; Am. J. Hum. Genet. 2008 Jun 82 (6): 1249-61.; Pubmed 18514161

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