GABPA Antibody - C-terminal region (P100832_T100)

Catalog No: P100832_T100

WB Suggested Anti-GABPA Antibody Titration: 0.5-1.0ug/ml
Positive Control: Jurkat cell lysateGABPA is supported by BioGPS gene expression data to be expressed in Jurkat

Host: Mouse
Target Name: GABPA
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml

Human kidney

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GABPA
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: KWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIG
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-GABPA (P100832_T100) antibody is Catalog # AAP31187 (Previous Catalog # AAPP01930)
• Sample Type Confirmation:

  GABPA is supported by BioGPS gene expression data to be expressed in Jurkat

Target Info

• Reference: Xue, H.H., et al., (2004) Nat.Immunol.5(10),1036-1044
• Gene Symbol: GABPA
• Gene Full Name: GA binding protein transcription factor, alpha subunit 60kDa
• Alias Symbols: NFT2, NRF2, NRF2A, E4TF1A, E4TF1-60, RCH04A07
• NCBI Gene Id: 2551
• Protein Name: GA-binding protein alpha chain
• Description of Target: GA Binding Protein . chain (GABP-. subunit, GABPA, nuclear respiratory factor-2 subunit . transcription factor E4TF1-60) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.
• Uniprot ID: Q06546
• Protein Accession #: NP_002031
• Nucleotide Accession #: NM_002040
• Protein Size (# AA): 454
• Molecular Weight: 51kDa
• Protein Interactions: UBC; NCOA7; KCTD12; TSEN34; DIABLO; CUTC; RAB3GAP2; LIMCH1; RAB3GAP1; GNE; KPNA1; YY1; GABPB1; PINX1; APP; KEAP1; SUMO2; HDAC1; EP300; SP3; CREBBP; HCFC1; SP1; ATF1; MED1;