GABPA Antibody - C-terminal region : HRP (P100832_T100-HRP)

Catalog No: P100832_T100-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: IHC, WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GABPA
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: KWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-GABPA (P100832_T100-HRP) antibody is Catalog # AAP31187 (Previous Catalog # AAPP01930)
• Sample Type Confirmation:

  GABPA is supported by BioGPS gene expression data to be expressed in Jurkat

• Reference: Xue, H.H., et al., (2004) Nat.Immunol.5(10),1036-1044

Target Info

• Gene Symbol: GABPA
• Gene Full Name: GA binding protein transcription factor, alpha subunit 60kDa
• Alias Symbols: NFT2, NRF2, NRF2A, E4TF1A, E4TF1-60, RCH04A07
• NCBI Gene Id: 2551
• Protein Name: GA-binding protein alpha chain
• Description of Target: GA Binding Protein . chain (GABP-. subunit, GABPA, nuclear respiratory factor-2 subunit . transcription factor E4TF1-60) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.
• Uniprot ID: Q06546
• Protein Accession #: NP_002031
• Nucleotide Accession #: NM_002040
• Protein Size (# AA): 454
• Molecular Weight: 51kDa
• Protein Interactions: UBC; NCOA7; KCTD12; TSEN34; DIABLO; CUTC; RAB3GAP2; LIMCH1; RAB3GAP1; GNE; KPNA1; YY1; GABPB1; PINX1; APP; KEAP1; SUMO2; HDAC1; EP300; SP3; CREBBP; HCFC1; SP1; ATF1; MED1;