G6PD Antibody - middle region (ARP58469_P050)

Catalog No: ARP58469_P050

WB Suggested Anti-G6PD Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysateG6PD is supported by BioGPS gene expression data to be expressed in MCF7

Host: Rabbit
Target Name: NSUN6
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human G6PD
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 85%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%; Sheep: 83%
• Peptide Sequence: Synthetic peptide located within the following region: VTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRI
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-G6PD (ARP58469_P050) antibody is Catalog # AAP58469 (Previous Catalog # AAPP34520)
• Sample Type Confirmation:

  G6PD is supported by BioGPS gene expression data to be expressed in MCF7

Target Info

• Reference: Langbein,S., (2008) Int. J. Cancer 122 (11), 2422-2428
• Gene Symbol: G6PD
• Gene Full Name: Glucose-6-phosphate dehydrogenase
• Alias Symbols: G6PD1
• NCBI Gene Id: 2539
• Protein Name: Glucose-6-phosphate 1-dehydrogenase
• Description of Target: G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: P11413
• Protein Accession #: NP_000393
• Nucleotide Accession #: NM_000402
• Protein Size (# AA): 515
• Molecular Weight: 57kDa
• Protein Interactions: G6PD; SUMO2; UBC; MDM2; CKB; CAPN1; ALDH7A1; ZNF622; ZFYVE19; UBFD1; CNDP2; ISOC1; MAT2B; ERP44; YWHAQ; SLC9A3R1; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; EIF4H; VCL; UBE2V1; TGM2; PPP1R2; PGD; PAK2; LDHB; SFN; GNS; GLA; GBP2; EIF5; BAG3; FN1; CCT4; HARS; SUMO4