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Datasheets/Manuals | Printable datasheet for G3BP1 Antibody (OACA06857) (OACA06857) |
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Predicted Species Reactivity | Human |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human Ras GTPase-activating protein-binding protein 1 protein (227-466AA) |
Purification | Affinity Purified |
Preservative | 0.02% sodium azide |
Formulation | PBS with, 50% glycerol, pH7.3. |
Reference | [1]"Crystal structure of the NTF2 domain of ras GTPase-activating protein-binding protein 1." Structural genomics consortium (SGC)Submitted (FEB-2011). [2]"Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells." Thedieck K., Holzwarth B., Prentzell M.T., Boehlke C., Klasener K., Ruf S., Sonntag A.G., Maerz L., Grellscheid S.N., Kremmer E., Nitschke R., Kuehn E.W., Jonker J.W., Groen A.K., Reth M., Hall M.N., Baumeister R.Cell 154:859-874(2013). [3]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.Sci. Signal. 4:RS3-RS3(2011). |
Gene Symbol | G3BP1 |
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Gene Full Name | G3BP stress granule assembly factor 1 |
Alias Symbols | ATP-dependent DNA helicase VIII;DNA helicase VIII;G3BP;G3BP-1;GAP binding protein;GAP SH3 domain-binding protein 1;GTPase activating protein (SH3 domain) binding protein 1;HDH-VIII;ras GTPase-activating protein-binding protein 1;RasGAP-associated endoribonuclease G3BP;Ras-GTPase-activating protein SH3-domain-binding protein. |
NCBI Gene Id | 10146 |
Protein Name | Ras GTPase-activating protein-binding protein 1 |
Description of Target | ATP- and magnesium-dependent helicase (PubMed:9889278). Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends (PubMed:9889278). Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency (PubMed:9889278). Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA (PubMed:9889278). Phosphorylation-dependent sequence-specific endoribonuclease in vitro (PubMed:11604510). Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR (PubMed:11604510). May be a regulated effector of stress granule assembly (PubMed:12642610, PubMed:20180778). |
Uniprot ID | Q13283 |
Protein Accession # | NP_005745 |
Nucleotide Accession # | NM_005754 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "G3BP1 Antibody (OACA06857)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "G3BP1 Antibody (OACA06857)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "G3BP1 Antibody (OACA06857)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "G3BP1 Antibody (OACA06857)"?
This target may also be called "ATP-dependent DNA helicase VIII;DNA helicase VIII;G3BP;G3BP-1;GAP binding protein;GAP SH3 domain-binding protein 1;GTPase activating protein (SH3 domain) binding protein 1;HDH-VIII;ras GTPase-activating protein-binding protein 1;RasGAP-associated endoribonuclease G3BP;Ras-GTPase-activating protein SH3-domain-binding protein." in publications.
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What is the shipping cost for "G3BP1 Antibody (OACA06857)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "G3BP1 Antibody (OACA06857)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "G3BP1 Antibody (OACA06857)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "G3BP1 Antibody (OACA06857)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "G3BP1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "G3BP1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "G3BP1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "G3BP1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "G3BP1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "G3BP1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.