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FZD9 Antibody (OABF00540)

100 ul
$359.00
In Stock
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Conjugation Options

OABF00540-FITC Conjugated

OABF00540-HRP Conjugated

OABF00540-Biotin Conjugated

Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Conjugation:
Unconjugated
Application:
FC, IHC-P
Additional Information:
Subcellular location: Extracellular
Reconstitution and Storage:
Store at -20C for 12 months.
Gene Symbol:
FZD9
Official Gene Full Name:
frizzled class receptor 9
NCBI Gene Id:
8326
Swissprot Id:
O00144
Alias Symbols:
FZD3, CD349,
Replacement Item:
This antibody may replace item sc-292864 from Santa Cruz Biotechnology.
Description of Target:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Purification:
Purified by Protein A.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FZD9.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FZD9.
Immunogen:
KLH conjugated synthetic peptide derived from human Frizzled 9/CD349
Concentration:
1ug/ul
Datasheets/Manuals:
Printable datasheet for OABF00540
Application Info:
FC: 1:20 - 100
IHC-P: : 1:100 - 500

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