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FZD10 Antibody (OAAJ05696)

100 uL
$289.00
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Gene Symbol:
FZD10
NCBI Gene Id:
11211
Protein Name:
Frizzled-10
Swissprot Id:
Q9ULW2
Protein Accession #:
NP_009128
Nucleotide Accession #:
NM_007197
Alias Symbols:
CD350, Frizzled-10, Fz10, Fz-10, FZ-10, FzE7, hFz10
Description of Target:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Molecular Weight:
60 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Immunogen affinity chromatography
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FZD10.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FZD10.
Immunogen:
A synthesized peptide
Predicted Species Reactivity:
Human, Mouse
Product Format:
Liquid
Reconstitution and Storage:
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Concentration:
1 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-FZD10 (OAAJ05696) antibody

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