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FYN Antibody (OASA00727)

0.1mg
$315.00
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Gene Symbol:
FYN
NCBI Gene Id:
2534
Protein Name:
Tyrosine-protein kinase Fyn
Swissprot Id:
P06241
Protein Accession #:
NP_002028.1
Alias Symbols:
SLK, SYN, MGC45350, FYN
Replacement Item:
This antibody may replace item sc-115186, HPA023887
Description of Target:
MOUSE ANTI FYN
Protein Size (# AA):
537
Host:
Mouse
Clonality:
Monoclonal
Application:
IHC-AFF, IP, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FYN.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FYN.
Immunogen:
The immunogen for anti-FYN antibody: bacterially expressed recombinant fragment of human fyn aa 7-176.
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Purified IgG - liquid
Reconstitution and Storage:
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody.
Datasheets/Manuals:
Printable datasheet for anti-FYN antibody - OASA00727
Specificity:
FYN
Clone:
FYN-01
Isotype:
IgG
Application Info:
(1)See [*] for special conditions.
Additional Information:
Histology Positive Control Tissue: Brain
:::
Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Preservative Stabilisers: 0.09% - Sodium Azide
:::
Approx Protein Conc: IgG concentration 1.0 mg/ml
Buffer Solutions: Phosphate buffered saline pH7.4
Target Reference:
1. Ho, G.J. et al. (2005) Altered p59Fyn kinase expression accompanies disease progression in Alzheimer 's disease: implications for its functional role. Neurobiol. Aging. 26: 625-35.
2. Lee, G. et al. (2004) Phosphorylation of Tau by Fyn: Implications for Alzheimer 's disease. J. Neuroscience 24:2304-12.
3. Olszowy, M.W. et al. (1995) Comparison of p56lck and p59fyn protein expression in thymocyte subsets, peripheral T cells, NK cells and lymphoid cell lines. J. Immunol. (1995). 155(9):4236-4240.
4. Zamoyska, R. et al. (2003) The influence of the src-family kinases Lck and Fyn, on T cell differentiation, survival and activation. Immunol. Rev. 191:107-118.

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