FXR2 Antibody - middle region (ARP40557_P050)

Catalog No: ARP40557_P050

WB Suggested Anti-FXR2 Antibody Titration: 0.2-1 ug/ml
Positive Control: MCF7 cell lysateFXR2 is supported by BioGPS gene expression data to be expressed in MCF7

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FXR2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: RGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRR
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-FXR2 (ARP40557_P050) antibody is Catalog # AAP40557 (Previous Catalog # AAPP22735)
• Sample Type Confirmation:

  FXR2 is supported by BioGPS gene expression data to be expressed in MCF7

• Reference: Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)

Target Info

• Gene Symbol: FXR2
• Gene Full Name: Fragile X mental retardation, autosomal homolog 2
• Alias Symbols: FXR2P, FMR1L2
• NCBI Gene Id: 9513
• Protein Name: Fragile X mental retardation syndrome-related protein 2
• Description of Target: FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P51116
• Protein Accession #: NP_004851
• Nucleotide Accession #: NM_004860
• Protein Size (# AA): 673
• Molecular Weight: 74kDa
• Protein Interactions: MORF4L1; FMR1; MRPL43; PRAM1; CEP44; HMBOX1; C1orf35; NIF3L1; TBC1D22B; CEP55; FAM90A1; PAF1; LASP1; POM121; FXR2; ZBTB22; AP1M1; SCEL; YES1; SRPK2; PIM1; PCBD1; MFAP1; LCP2; CDKL3; BAZ2B; CAMK2D; BYSL; C10orf62; MIA3; ZMAT2; SYT6; SYTL4; NDN; KIF1A; UBC;