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FUBP1 antibody - N-terminal region (ARP37732_T100)

100 ul
$229.00
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Conjugation Options

ARP37732_T100-FITC Conjugated

ARP37732_T100-HRP Conjugated

ARP37732_T100-Biotin Conjugated

Gene Symbol:
FUBP1
NCBI Gene Id:
8880
Official Gene Full Name:
Far upstream element (FUSE) binding protein 1
Protein Name:
Far upstream element-binding protein 1
Swissprot Id:
Q96AE4
Protein Accession #:
NP_003893
Nucleotide Accession #:
NM_003902
Alias Symbols:
FBP, FUBP
Replacement Item:
This antibody may replace item sc-11098 from Santa Cruz Biotechnology.
Description of Target:
Far upstream element-binding protein activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. FUBP activity may be regulated by alternative splicing, translation efficiency, and posttranslational modification.
Protein Size (# AA):
644
Molecular Weight:
68kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FUBP1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FUBP1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human FUBP1
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-FUBP1 (ARP37732_T100)
Peptide Sequence:
Synthetic peptide located within the following region: IGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEM
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; MDM2; EED; DDX19A; NSUN2; PLD3; ARPC2; ACTR2; ACTR3; ARPC4; HIST1H2BO; SH3GL1; RPA1; PPP5C; LGALS1; CNN2; BAG1; ACO1; AARSD1; GRPEL1; NIF3L1; RPRD1B; CD81; ITGA4; FN1; ATF2; AIMP2; VCAM1; DHX36; MRPL32; MRPL38; MRPL41; MRPL2; CERS2; MRPL42; MRPL46; P
Blocking Peptide:
For anti-FUBP1 (ARP37732_T100) antibody is Catalog # AAP37732 (Previous Catalog # AAPP08814)
Datasheets/Manuals:
Printable datasheet for anti-FUBP1 (ARP37732_T100) antibody
Sample Type Confirmation:

FUBP1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Target Reference:
Duncan,R., et al., (1994) Genes Dev. 8 (4), 465-480
Publications:

Zheng, W; Shen, F; Hu, R; Roy, B; Yang, J; Wang, Q; Zhang, F; King, JC; Sergi, C; Liu, SM; Cordat, E; Tang, J; Cao, Y; Ali, D; Chen, XZ; Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation. 27, 2645-57 (2016). WB, IHC, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 26839368

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